Self Renewal of Spermatogonial Stem Cells: the Most Promising Multipotent Cells - A Review

Tokas, J.; Mukhopadhyay, C.S. and Verma, Archana (2011) Self Renewal of Spermatogonial Stem Cells: the Most Promising Multipotent Cells - A Review. Veterinary World, 4 (5). pp. 234-240. ISSN 0972-8988, EISSN 2231-0916

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Abstract

Germ cells are endowed with unique properties like the ability to undergo meiosis and differentiate into gametes in order to perpetuate the genetic material. Spermatogonial stem cells (SSC) are considered as the best suited undifferentiated germ cells and are being consistently studied to reveal the basic physiology, genomics and transcriptomics of those cells. SSC provide an excellent model system to understand the differentiation, development and functioning of gonads and further use of these cells in transplantation-cell based therapies. In the present article, basic aspects of spermatogonial multiplication, regulation of stem cell renewal and differentiation would be discussed.

EPrint Type:Article
Uncontrolled Keywords:Spermatogonial stem cells, spermatogenesis, testis, self-renewal.
Subjects:Cells > Stem Cells
-Journal Repositories > Veterinary World
ID Code:3679
Deposited By:Dr Anjum Sherasiya
Deposited On:26 July 2011

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