Blood transfusions: are they life saving or transfusing infections?

Amrutha Kumari, B.; Deepa, S. and Venkatesha, D. (2011) Blood transfusions: are they life saving or transfusing infections? Online Journal of Health and Allied Sciences, 10 (2). ISSN 0972-5997

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Introduction: There is a risk of 1 - 2 per 1000 recipients receiving contaminated blood with viral, bacterial and parasitic agents.TTI’S are the most commonly encountered complications in transfusion medicine. The objective of the study was to determine the seroprevalence of TTI’s among blood donors, who represent healthy population at large. Materials & methods: A total of 33,658 blood units were received from voluntary and replacement donors over a period of 5 years. Surface antigen of HBV and antibodies to HIV and HCV were determined using ELISA. Syphilis was detected using TPHA test. Results: 947 (2.81%) blood units tested positive for HBV, HCV, HIV and / or syphilis. Overall prevalence was HBV – 1.77%, HCV – 0.13%, HIV – 0.63% and Syphilis – 0.28%. Nine (0.03%) donors had coinfections. Conclusion: The screening of blood donors is the corner stone in assuring the safety of blood transfusion.

EPrint Type:Article
Uncontrolled Keywords:Transfusion Transmitted Infections; HBV; HCV; HIV; Syphilis
Subjects:Circulatory and Respiratory Physiology > Blood Physiology
Therapeutics > Biological Therapy
Hematologic, Gastrointestinal, and Renal Agents > Hematologic Agents > Blood Substitutes
-Journal Repositories > Online Journal of Health and Allied Sciences
Bacteria > Blood-Borne Pathogens
Hemic and Immune Systems > Blood
Archaea > Blood-Borne Pathogens
Fungi > Blood-Borne Pathogens
Algae > Blood-Borne Pathogens
ID Code:3808
Deposited By:Dr Srinivas Kakkilaya
Deposited On:11 September 2012

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