Freeze dried BCG vaccine sealed in presence of nitrogen

Bhushan, Kul; Baily, G.V.J.; Nair, S.S.; Ganapathy, K.T. and Singh, Vijay (1975) Freeze dried BCG vaccine sealed in presence of nitrogen. Indian Journal of Medical Research, 63 (9). pp. 1335-1343.

Full text available as:

PDF - Requires Adobe Acrobat Reader or other PDF viewer.
215 Kb

Abstract

Because of the obvious operational economical, and technical advantages of the freeze dried BCG vaccine sealed in presence of nitrogen, it was compared with the standard freeze-dried BCG vaccine sealed in vacuum, when stored at different temperatures (4oC. 37oC., and 44oC.) for 2, 6 and 18 weeks each. It was found that in terms of post-vaccination allergy and size of vaccination lesion, the vaccines sealed by either method were not affected when stored at 4oC up to l8 weeks or at 37°C for two weeks. For other periods both types of vaccines were affected badly when stored at 37°C and for any period at 44°C. Viable counts for the vaccine sealed in presence of nitrogen, however, reduced rapidly with time.

EPrint Type:Article
Uncontrolled Keywords:Freeze dried BCG, Nitrogen, BCG Vaccine
Subjects:-Institutional Repositories > National Tuberculosis Institute
Inorganic Chemicals > Elements > Nitrogen
Therapeutics > Biological Therapy > Immunotherapy > Immunization > Immunotherapy, Active > Vaccination
Investigative Techniques > Preservation, Biological > Cryopreservation
Immunologic and Biological Factors > Biological Products > Vaccines > Bacterial Vaccines > Tuberculosis Vaccines > BCG Vaccine
ID Code:412
Deposited By:Librarian Sudha S Murthy
Deposited On:28 July 2005

Archive Staff Only: edit this record