Use of 20 TU RT 23 and 5 TU battery antigen for estimation of prevalence of non-specific tuberculin sensitivity

Gothi, G.D.; Chakraborty, A.K.; Jayalakshmi, M.J. and Ganapathy, K.T. (1977) Use of 20 TU RT 23 and 5 TU battery antigen for estimation of prevalence of non-specific tuberculin sensitivity. Indian Journal of Medical Research, 66 (3). pp. 389-397.

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Abstract

Estimates of prevalence of non-specific tuberculin sensitivity in south Indian population are based on studies using large doses of tuberculin prepared from Mycobacterium tuberculosis. In the present study on 2168 children aged 0-9 years in rural areas, distribution of induration to 20 TU RT 23 test has been compared to that of 5 TU Battey test, to see whether estimates of prevalence of non-specific tuberculin sensitivity based on the former could be compared with those based on tests with antigen derived from other mycobacteria. It was seen that distributions of reactions, mean size of indurations as well as percentage of positive reactors to test were not significantly different in the two randomly selected groups i.e. one tested with Battey antigen and the other with 20 TU RT 23. The prevalence of nonspecific sensitivity 0-4 years age group based on Battey test was 18.4 per cent and that 20 TU test 16.6 per cent. In the age group 5-9 years corresponding rates were 54.2 and 60.1 per cent. From these observations, it is suggested that if other antigens are not available, 20 TU RT 23 could be used for estimation of non-specific sensitivity.

EPrint Type:Article
Uncontrolled Keywords:Sensitivity and Specificity, Mycobacterium tuberculosis, Tuberculin Sensivity
Subjects:Bacterial Infections and Mycoses > Bacterial Infections > Gram-Positive Bacterial Infections > Actinomycetales Infections > Mycobacterium Infections > Tuberculosis
-Institutional Repositories > National Tuberculosis Institute
Bacterial Infections and Mycoses > Bacterial Infections > Gram-Positive Bacterial Infections > Actinomycetales Infections > Mycobacterium Infections
Diagnosis > Diagnostic Techniques and Procedures > Skin Tests > Tuberculin Test
Immunologic and Biological Factors > Immunologic Factors > Antigens
ID Code:414
Deposited By:Librarian Sudha S Murthy
Deposited On:28 July 2005

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