Treatment dynamics and profile of tuberculosis patients under the district tuberculosis programme (DTP): a prospective cohort study
Vijay, Sophia; Balasangameshwara, V.H. and Srikantaramu, N. (1999) Treatment dynamics and profile of tuberculosis patients under the district tuberculosis programme (DTP): a prospective cohort study. Indian Journal of Tuberculosis, 46. pp. 239-250.
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A prospective cohort study among new smear positive pulmonary tuberculosis cases initiated on short course chemotherapy was undertaken in Kolar district of Karnataka. The objective was to study the treatment outcome and patient profiles of treatment adherent (completed) and non-adherent (lost) patients. Data collection was done through interviews based on pretested structured schedules, soon after diagnosis and at the end of treatment. Of the 224 available patients in the cohort, 120 (53.6%) completed treatment, 68 (30.4%), were lost, 29 (12.9%) died and 7 (3.1 %) migrated outside the district. Persistence of cough at the end of treatment was significantly more among lost patients. The general profile of the patients, relating to socio-economic, demographic, literacy and employment details did not differ significantly between the 2 subgroups. However, the treatment related factors like distance from health centre, Knowledge of treatment duration, advice on treatment given after diagnosis, payments made to staff and for tonics were significantly more among patients lost to treatment. Raising of money to meet the expenditure, particularly through selling of valuables too was proportionately more among lost patients. Defaulter retrieval action was not taken for more than 85% of all eligibles, both among completed and lost groups.
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