Short course chemotherapy and efeiciency variables in National Tuberculosis Programme: a model
Chakraborty, A.K.; Balasangameshwara, V.H.; Jagota, P.S.; Sreenivas, T.R. and Chaudhuri, K. (1992) Short course chemotherapy and efeiciency variables in National Tuberculosis Programme: a model. Indian Journal of Tuberculosis, 39. pp. 9-20.
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The mathematical model presented here brings out the role of various levels of efficiency in the performance of key tuberculosis control activities in the light of the introduction of short course chemotherapy (SCC) under the District Tuberculosis Programme (DTP) in India. It shows that the potential of DTP could be realised only when all the various activities are performed with a high degree of efficiency. And that ACC alone cannot appreciably alter the DTP efficiency expectations. For example, DTP efficiency with SCC, even when 100% of patients take more than 80% of the prescribed drugs increases only to 29% with SCC, over 24% with standard chemotherapy (SR), if case-finding efficiency (CF efficiency) remains unchanged at 33%, which is its current level. A “critical DTP efficiency” i.e., the efficiency of the various DTP activities that could lead to sputum conversion of 85% of the cases diagnosed requires the performance of key activities at a high level namely, CF efficiency of 100%, cases put on SCC l00% and the compliance structure of 70% in level four and 20% in level three. Thus, DTP shall have to be geared to meet high performance requirements to achieve its avowed objectives. The model gives various levels expectations as the outcome of DTP, relating to changes in efficiency estimates of the key DTP activities.
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