Recovery of tubercule bacilli from urine of pulmonary tuberculosis patients and its comparison with the corresponding sputum isolates

Challu, V.K.; Mahadev, B.; Rajalakshmi, R. and Chaudhuri, K. (1989) Recovery of tubercule bacilli from urine of pulmonary tuberculosis patients and its comparison with the corresponding sputum isolates. Indian Journal of Tuberculosis, 36 (2). pp. 107-111.

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Abstract

Urine specimens from 236 pulmonary tuberculosis patients were cultured by routine centrifugation method and by a method depending on filtration through a membrance filter. Mycobacterium tuberculosis was recovered from 35 (14.8%) of the urines either by the filtration method, the centrifugation method or by both. Eight of 35(22.8%) of urine cultures, negative by the centrifugation method, were positive by filtration method. Comparison of the biologic properties of M.tuberculosis isolated from urine and sputum of the same individual revealed difference in drug sensitivity profiles or virulence for guinea pigs for 13 of 25 (52%) of the pairs of isolates tested. Moreover, four of 11 pairs isolates subjected to phage typing were found to differ in both major and minor phage types.

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