Results of treatment with a short course chemotherapy regimen used field conditions in District Tuberculosis Programme

Chaudhuri, K.; Jagota, P. and Parimala, N. (1993) Results of treatment with a short course chemotherapy regimen used field conditions in District Tuberculosis Programme. Indian Journal of Tuberculosis, 40. pp. 83-89.

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Abstract

The treatment results of an unsupervised Short Course Chemotherapy (SCC) regimen used under conditions of District Tuberculosis Programme (DTP) are presented. The District Tuberculosis Centre (DTC) Kolar and six of its peripheral health institutions (PHI) formed the study area. No extra efforts except ensuring of adequate availability of drugs at the participating centers were made to obtain patients’ compliance. In all, 584 smear positive tuberculosis patients were diagnosed during the study period but 28.3% of the patients could not be initiated on treatment with the chosen self-administered SCC regimen- 2EHRZ/6TH (EH). Of the 382 put on treatment, only 33.2% completed over 75% drug collections in both intensive and continuation phases. The pattern of treatment compliance did not vary with the place of treatment, i.e. DTC & PHI. Irrespective of treatment compliance, nearly 72-77% of the patients attained smear negative status at the end of the period of treatment, there being no difference between PHI and DTC. However, deaths were higher in the PHI patients. This could be attributed to a significantly higher proportion of aged patients taking treatment at PHI than at DTC. Patients with drug sensitive bacilli had a higher rate of culture negativity (70%) as compared to those with drug resistant bacilli (48%). It was concluded that unsupervised SCC could give encouraging results in a DTP setting provided adequate drug supply was ensured.

EPrint Type:Article
Uncontrolled Keywords:Short Course Chemotherapy, Field Conditions, Tuberculosis Programme, Unsupervised Chemotherapy
Subjects:Bacterial Infections and Mycoses > Bacterial Infections > Gram-Positive Bacterial Infections > Actinomycetales Infections > Mycobacterium Infections > Tuberculosis
Therapeutics > Drug Therapy
-Institutional Repositories > National Tuberculosis Institute
Health Care Economics and Organizations > Health Planning > National Health Programs
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Investigative Techniques > Drug Administration Schedule
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:658
Deposited By:Librarian Sudha S Murthy
Deposited On:09 August 2005

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