Treatment of chronic non-co-operative patients with isonictonic hydrazide p-aminosalicylate: a co-operative study by the tuberculosis institutions in Delhi

Pamra, S.P. (1962) Treatment of chronic non-co-operative patients with isonictonic hydrazide p-aminosalicylate: a co-operative study by the tuberculosis institutions in Delhi. Indian Journal of Tuberculosis, 9 (4). pp. 204-210.

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Abstract

A co-operative trial was conducted by the five Tuberculosis institutions in Delhi to assess the activity of Isonicotinic Hydrazide-p- Aminosalicylate in treatment of pulmonary tuberculosis. Two hundred and thirty-one chronic patients were included in the trial. Nearly one-fourth were left untreated, another one-fourth were given I.N.H. and the remaining had two different brands of the salt viz., Pasinh and Isopar. Results of 200 patients who had more than six months’ treatment were analysed in respect of sputum conversion, cavity closure, radiological and weight changes, and sensitivity of bacilli (latter in 130 patients only). All groups behaved almost similarly in these respects and Isonicotinic Hydrazide-p- Aminosalicylate appeared in no way superior to I.N.H. in the type of cases included in the trial.

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