A simple paper test for isoniazid in urine

Gangadharam, P. R. J.; Narayanan Nair, C. and Subbiah, T.V. (1962) A simple paper test for isoniazid in urine. Indian Journal of Tuberculosis, 9 (4). pp. 219-223.

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A paper test modification of the direct naphthoquinone-mercuric chloride (N-M) test developed in this Centre has been compared with a similar paper test described by Cattaneo etal. (1960), and with the previously described direct and combined N-M tests. The paper test was, if anything, slightly more sensitive than the Cattaneo paper test and the direct N-M test but considerably less sensitive than the combined N-M test. However, the paper test detected isoniazid in all the urine specimens obtained from one to six hours from 20 volunteers who had taken a single dose of approximately 6.7 mg. isoniazid per kg. body-weight. The application of the paper test for use in chest clinics and under field conditions has been discussed.

EPrint Type:Article
Uncontrolled Keywords:Paper Test, Urine, Isoniazid, Hydrolysis naphthoquinone-mercuric chloride test, Naphthoquinone-mercuric chloride paper test, Urine test
Subjects:Organic Chemicals > Quinones > Naphthoquinones
Organic Chemicals > Hydrazines > Isoniazid
Fluids and Secretions > Body Fluids > Urine
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Inorganic Chemicals > Mercury Compounds > Mercuric Chloride
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
Diagnosis > Laboratory Techniques and Procedures
ID Code:940
Deposited By:Mrs Naina Pandita
Deposited On:19 September 2005

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