Corticosteroid therapy in chronic drug resistant tuberculosis
Menon, N.K. (1964) Corticosteroid therapy in chronic drug resistant tuberculosis. Indian Journal of Tuberculosis, 11 (2). pp. 69-81.
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Twenty patients with chronic far advanced disease and cultures resistant to all the three standard drugs were given prednisolone for 3 months in addition to the three antituber- culosis drugs which they were already receiving. 9 patients showed slight to moderate X-ray regression; 8 had their radiographic deteriora- tion arrested and all reported considerable sub- jective improvement. When reviewed 3 months after prednisolone had been stopped, 15 out of these 17 cases were found to have maintained their clinical and radiographic gains. No instance of significant radiographic deteriora- tion attributable to prednisolone was seen. rioration attributable to prednisolone therapy had been noticed in any of the 20 cases treated.
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