Corticosteroids in the treatment of tuberculous pleural effusion
Grewal, K.S.; Dixit, R.P. and Dutta, B. (1964) Corticosteroids in the treatment of tuberculous pleural effusion. Indian Journal of Tuberculosis, 11 (4). pp. 177-181.
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61 Cases of tuberculous pleural effusion, on three different treatment regimens, have been studied. Group I: Antimicrobial drugs + corticosteroid (30 cases). Group II. Antimicrobial drugs (19 cases). Group III: Antimicrobial drugs-)- Repeated aspiration (12 cases). The comparative results of treatment at 15 days, and 1, 3, 6 months indicate that (1) Clinical improvement as judged by abolition of fever, gain in weight and fall in E.S.R. is more rapid in the steroid group. (2) Radiological clearance at all stages and particularly at 15 days and 1 month shows a statistically significant difference in favour of the steroid group. This is particularly marked when the effusions are upto and above the hilum level. The incidence of shadows of thickened pleura and obliteration of costophrenic angle is significantly lower in the steroid group. The complications due to steroids are few and minor.
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