The relative merits of various virulence tests for mycobacteria

Mahapatra, B. (1964) The relative merits of various virulence tests for mycobacteria. Indian Journal of Tuberculosis, 11 (4). pp. 172-176.

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One hundred and twenty-five strains of mycobacteria freshly isolated from clinical cases of pulmonary tuberculosis were sub- jected to animal pathogenicity, cording and neutral-red tests in order to establish their relative virulence. In another 6.4 per cent strains our findings were rather unusual. These strains were INH resistant, all forming poor quality of cords and three showing negative mice pathogenicity. The probability for such unusual result is explained. Since all the tests show variation, a better evaluation of virulence can be made by studying more than one property rather than any single one. The combined study of cytochemical reaction and cord formation gives as much information as animal pathogenicity with definite advantage and can be adopted in practice.

EPrint Type:Article
Uncontrolled Keywords:Virulence Tests, Mycobacteria strains, Pathogenecity, Cording Effect
Subjects:Equipment and Supplies > Culture Media
Bacteria > Gram-Positive Bacteria > Actinobacteria > Actinomycetales > Mycobacteriaceae > Mycobacterium
Investigative Techniques > Animal Experimentation
Investigative Techniques > Models, Animal
Investigative Techniques > Clinical Laboratory Techniques > Culture Techniques
Immunologic and Biological Factors > Biological Factors > Virulence Factors
Biochemical Phenomena, Metabolism, and Nutrition > Biochemical Phenomena
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:978
Deposited By:Mrs Naina Pandita
Deposited On:02 December 2005

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