Susceptibility of guinea pig to Mycobacterium tuberculosis

Shriniwas, Dr. (1965) Susceptibility of guinea pig to Mycobacterium tuberculosis. Indian Journal of Tuberculosis, 13 (1). pp. 27-33.

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Abstract

Eighteen guinea-pigs (8 male and 10 female) from 3 different sources were obtained for the study. Mycobacterium tuberculosis H37 Rv. strain in doses of 0.1 mgm. was injected intraperitoneally to see its effect on the animals. All the animals died of progressive tuberculosis between 27 to 30 days after challenge infection. On autopsy varying degree of tuber- cular lesions were observed in all the animals irrespective of their source of supply.Weight loss was a significant finding in all the animals.

EPrint Type:Article
Uncontrolled Keywords:Susceptibility, Guinea Pigs, Mycobacterium tuberculosis, Mantoux tuberculin test, Weight loss, Death
Subjects:Pathological Conditions, Signs and Symptoms > Pathologic Processes > Disease Attributes
Pathological Conditions, Signs and Symptoms > Pathologic Processes > Death
Bacteria > Gram-Positive Bacteria > Actinobacteria > Actinomycetales > Mycobacteriaceae > Mycobacterium > Mycobacterium tuberculosis
Investigative Techniques > Animal Experimentation
Animals > Chordata > Vertebrates > Mammals > Rodentia > Guinea Pigs
Diagnosis > Diagnostic Techniques and Procedures > Skin Tests > Tuberculin Test
Pathological Conditions, Signs and Symptoms > Signs and Symptoms > Body Weight Changes
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:986
Deposited By:Mrs Naina Pandita
Deposited On:21 October 2005

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