Thiacetazone jaundice: case reports

Narang, P.K. and Sarin, J.N. (1966) Thiacetazone jaundice: case reports. Indian Journal of Tuberculosis, 13 (2). pp. 77-78.

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Three cases of jaundice due to thiacetazone are reported. Infective hepatitis was excluded by liver biopsy in two cases. All the three cases were chronic advanced drug resistant cases of pulmonary tuberculosis and had malnutrition. The incidence of thiacetazone jaundice in such cases was 3.8%. No case of jaundice occurred in thiacetazone treatment of previously untreated patients. It is suggested that chronic malnutrition and chronic anoxia are important factors in predisposition to thiacetazone, hepatotoxicity.

EPrint Type:Article
Uncontrolled Keywords:Thiacetazone, Jaundice, Infective Hepatitis, Case Reports, Heptatoxicity, Drug Resistance, Malnutrition, Liver Biopsy
Subjects:Disorders of Environmental Origin > Poisoning > Drug Toxicity
Therapeutics > Drug Therapy
Chemical and Pharmacologic Phenomena > Drug Resistance
Surgical Procedures, Operative > Biopsy
Digestive System Diseases > Liver Diseases > Hepatitis
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Disorders of Environmental Origin > Poisoning > Hepatitis, Toxic
Persons > Age Groups > Adult
Organic Chemicals > Sulfur Compounds > Thiosemicarbazones
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
Nutritional and Metabolic Diseases > Nutrition Disorders > Malnutrition
Digestive System Diseases > Liver Diseases
ID Code:990
Deposited By:Mrs Naina Pandita
Deposited On:16 September 2005

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