Thiacetazone jaundice: case reports
Narang, P.K. and Sarin, J.N.
Thiacetazone jaundice: case reports.
Indian Journal of Tuberculosis, 13 (2).
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Three cases of jaundice due to thiacetazone are reported. Infective hepatitis was excluded by liver biopsy in two cases. All the three cases were chronic advanced drug resistant cases of pulmonary tuberculosis and had malnutrition. The incidence of thiacetazone jaundice in such cases was 3.8%. No case of jaundice occurred in thiacetazone treatment of previously untreated patients. It is suggested that chronic malnutrition and chronic anoxia are important factors in predisposition to thiacetazone, hepatotoxicity.
|Uncontrolled Keywords:||Thiacetazone, Jaundice, Infective Hepatitis, Case Reports, Heptatoxicity, Drug Resistance, Malnutrition, Liver Biopsy|
|Subjects:||Disorders of Environmental Origin > Poisoning > Drug Toxicity|
Therapeutics > Drug Therapy
Chemical and Pharmacologic Phenomena > Drug Resistance
Surgical Procedures, Operative > Biopsy
Digestive System Diseases > Liver Diseases > Hepatitis
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Disorders of Environmental Origin > Poisoning > Hepatitis, Toxic
Persons > Age Groups > Adult
Organic Chemicals > Sulfur Compounds > Thiosemicarbazones
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
Nutritional and Metabolic Diseases > Nutrition Disorders > Malnutrition
Digestive System Diseases > Liver Diseases
|Deposited By:||Mrs Naina Pandita|
|Deposited On:||16 September 2005|
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