The optimum dosage, rhythm and duration of isoniazid therapy in pulmonary tuberculosis
Devadatta, S. (1966) The optimum dosage, rhythm and duration of isoniazid therapy in pulmonary tuberculosis. Indian Journal of Tuberculosis, 13 (4). pp. 158-167.
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Isoniazid is the most effective, cheapest and most widely used drug in the chemotherapy of pulmonary tuberculosis. The optimum dosage, rhythm and duration of therapy with this drug are those which are maximally effective with minimal risk of toxicity. This paper is based mainly on studies carried out at the Tubercu- losis Chemotherapy Centre, Madras, India and also, to a lesser extent, on those in Great Britain and East Africa. It discusses the implication of these studies on isoniazid therapy for the developing as well as for the economically favoured countries and indicates possible lines for future investigations.
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