The optimum dosage, rhythm and duration of isoniazid therapy in pulmonary tuberculosis

Devadatta, S. (1966) The optimum dosage, rhythm and duration of isoniazid therapy in pulmonary tuberculosis. Indian Journal of Tuberculosis, 13 (4). pp. 158-167.

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Abstract

Isoniazid is the most effective, cheapest and most widely used drug in the chemotherapy of pulmonary tuberculosis. The optimum dosage, rhythm and duration of therapy with this drug are those which are maximally effective with minimal risk of toxicity. This paper is based mainly on studies carried out at the Tubercu- losis Chemotherapy Centre, Madras, India and also, to a lesser extent, on those in Great Britain and East Africa. It discusses the implication of these studies on isoniazid therapy for the developing as well as for the economically favoured countries and indicates possible lines for future investigations.

EPrint Type:Article
Uncontrolled Keywords:Optimum Dosage, Rhythm, Duration, Isoniazid, Pulmonary Tuberculosis, Treatment, Toxicity, Chemotherapy, Drug Combinations
Subjects:Disorders of Environmental Origin > Poisoning > Drug Toxicity
Therapeutics > Drug Therapy
Organic Chemicals > Hydrazines > Isoniazid
Investigative Techniques > Drug Administration Routes
Respiratory Tract Diseases > Respiratory Tract Infections > Tuberculosis, Pulmonary
Pharmaceutical Preparations > Drug Combinations
Chemical and Pharmacologic Phenomena > Dose-Response Relationship, Drug
Investigative Techniques > Drug Administration Schedule
Respiratory Tract Diseases > Lung Diseases > Tuberculosis, Pulmonary
-Journal Repositories > Indian Journal of Tuberculosis
ID Code:996
Deposited By:Mrs Naina Pandita
Deposited On:13 December 2005

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